An overview of hyperpolarized
helium-3 magnetic resonance
|
Michèle Leduc
|
1 |
|
I- Human and animal airways - from top to bottom - from
healthy to affected
1- Basics of lung morphology and physiology
a- Volumes and flows
b- Gas exchange
Laboratory: Pulmonary function
tests |
Jim Grötberg
(Michigan, United-States)
|
1 |
2- Basics of respiratory fluid mechanics
a-Convective transport
b-Diffusive transport |
1 |
3- Basics of lung mechanics
a- Mechanical propertie
b- Tension and surfactant
|
1
|
|
c- Basics of lung pathology
|
Gilles Garcia
(Clamart, France)
|
1 |
4- Basics of animal models - human
disease related
a- Basics of lung morphology and physiology
|
Jorge Boczkowski
(Créteil, France) |
1 |
|
b- Basic disease models |
Germán Peces-Barba
(Madrid, Spain)
|
1 |
|
II- Modelling of the respiratory system - from top to
bottom - from healthy to affected
1- Air flow models
a- Poiseuille flow in a self-similar tree
b- Gas transport into the acini
c- Gas diffusion in the peripheral airways
|
Marcel Filoche
(Palaiseau, France) |
1 |
|
2- Morphological models
a- Mathematical models of the bronchial tree
b- Mathematical models of the acinus |
Denis Grebenkov
(Palaiseau, France) |
1 |
|
III- Standard lung imaging techniques
1- Multiple
inert gas elimination technique (MIDGET)
2- Nuclear medicine (SPECT and PET)
Laboratory: Lung scintigraphy
3-
Chest X-ray and Computed Tomography
4-
Ultrasound imaging
5-
Standard proton MRI |
Edwin van Beek
(Iowa, United
States) |
2 |
|
IV Basics of hyperpolarisation
1- Spin-exchange optical pumping - helium-3 and xenon-129
|
Pierre-Jean Nacher
(Paris,
France) |
1 |
|
2- Metastability-exchange optical pumping - helium-3
Laboratory: On-site production |
1 |
V- Magnetic resonance imaging
1- Basics of nuclear magnetic resonance
a- Effective magnetic field in the rotating frame
b- Classical approach
c- Quantum mechanical approach
|
Zbigniew Olejniczak
(Krakow, Poland) |
1 |
|
2- Basics of scanner design
a- Permanent, resistive, and superconductive magnets |
Tadeuz Palaz
(Krakow, Poland) |
1 |
|
b- Measurement and imaging of the stationary magnetic field
c- Shimming coil design
d- Calculation and optimization methods
e- Gradient systems |
Ivan Frollo
(Bratislava, Slovakia) |
1 |
f- Radiofrequency emission and reception
i- Basic electromagnetism
ii- SNR and SAR
iii- The reciprocal principal
iv-
Simple tuning and matching
v-
Basic RF coil geometries
Laboratory: Tuning, matching and
Q-measurement practice with a surface coil |
Luc Darrasse
(Orsay-Bicêtre, France)
|
2 |
|
3- Image formation
a- Signal localisation
b- Basics of k-space
|
Jacques Bittoun
(Orsay-Bicêtre,
France)
|
2 |
|
4- Basic pulse sequences for hyperpolarised gases
a- Gradient echo
b- T1 and T2 weighting |
Jim Wild
(Sheffield, United
Kingdom)
|
2 |
|
VI- Human lung exploration with helium-3 magnetic
resonance
1- General lung imaging and clinical study management
|
Neil Woodhouse
(Sheffield, United
Kingdom) |
1 |
2- Ventilation images
a- Basic protocols
Laboratory: Helium-3 lung imaging on a Philips Achieva 1.5 T MRI scanner
|
Wolfgang Schreiber
(Mainz, Germany) |
1 |
b- Diffusion measurements
c- Partial oxygen pressure maps
|
Wolfgang Schreiber
(Mainz, Germany) |
1 |
|
3- Dynamic images
4- Flow measurements |
Emmanuel Durand
(Orsay-Bicêtre, France)
|
1 |
