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Lung Imaging
with Hyperpolarised Helium-3 Magnetic Resonance
- from gas production to medial application -
General training school
January 21-26 2008
Paris, France
   

Scope of the school

This school will address the highly multidisciplinary research field that sustains lung imaging with hyperpolarised helium-3. It will benefit from the rich inputs, knowledge and know-how, of the academic and industrial partners of the European network PHeLINet. It is meant for early stage as well as experienced researchers who enter the field - students and researchers in physics, biophysics, and medicine, medical doctors.

Tutorials will cover the principles of gas production and management, the developments of instruments and methods for magnetic resonance imaging, and the description of healthy and diseased human and animal airways. Lectures will also provide a current overview of the field as bases of discussions among participants, students, teachers, and researchers, which will be encouraged in order to share and understand the various knowledge and know-how needed and valued here.

This school will set the grounds for an advanced PHeLINet training school in May 26-31 2008 in Madrid, Spain.

Scientific committee 

  • Yannick Crémillieux (LRMN, CNRS, Univ. Claude Bernard, Lyon, France)
  • Luc Darrasse (U2R2M, CNRS, Univ. Paris-Sud, Orsay, France)
  • Werner Heil (Institut für Physik, Univ. Mainz, Germany)
  • Jesús Ruiz-Cabello (IEB, Univ. Complutense, Madrid, Spain)
  • Wolfgang Schreiber (Medical Physics, Univ. Mainz, Germany)
  • Jim Wild (Academic Radiology, Univ. Sheffield, United-Kingdom) 

Organization of the school

The school will be essentially based on tutorials. The basics and the techniques of the fields that are involved in hyperpolarised helium-3 magnetic resonance will be covered before exploring the multiple possibilities that the latter actually offer to lung physiology and pathology. To ease understanding and stimulate exchanges between lecturers and participants, these tutorials will be divided into one-hour sessions separated by 15 minutes breaks.
In addition, practical workshops will be held in small groups in Parisian hospitals and laboratories of PHeLINet partners.  They will assert the plenary lectures and feed a brainstorming session on crucial issues in hyperpolarised helium-3 magnetic resonance.
Finally, informal exchanges will be favoured around Parisian tables. 90 minutes will be left for lunches in selected Parisian restaurants. A dinner will welcome you on Sunday evening and the lunch on Saturday will say au revoir. An afternoon will be set free for extra activities.

Lecturers

  • Edwin van Beek (Department of Radiology, Univ. Iowa, United States)
  • Jacques Bittoun (U2R2M, CNRS, Univ. Paris-Sud, Orsay, France)
  • Luc Darrasse (U2R2M, CNRS, Univ. Paris-Sud, Orsay, France)
  • Emmanuel Durand (U2R2M, CNRS, Univ. Paris-Sud, Orsay, France)
  • James Grotberg (Biomechanical Engineering Depart., Univ. Michigan, United-States)
  • Denis Grebenkov (PMC, Ecole Polytechnique, Palaiseau, France)
  • Marcel Filoche (PMC, Ecole Polytechnique, Palaiseau, France)
  • Ivan Frollo (Institute of Measurement Science, Bratislava, Slovakia)
  • Gilles Garcia (Hôpital Antoine Béclère, Univ. Paris-Sud, Clamart, France)
  • Michèle Leduc (Laboratoire Kastler Brossel, ENS, Paris, France)
  • Germán Peces-Barba (IEB, Univ. Complutense, Madrid, Spain)
  • Pierre-Jean Nacher (Laboratoire Kastler Brossel, ENS, Paris, France)
  • Zbigniew Olejniczak (Institute of Physics, Univ. Jagellonian, Krakow, Poland)
  • Tadeuz Palaz (Institute of Physics, Univ. Jagellonian, Krakow, Poland)
  • Wolfgang Schreiber (Department of Radiology, Univ. Mainz, Germany)
  • Jim Wild (Academic Radiology, Univ. Sheffield, United-Kingdom)
  • Neil Woodhouse (Academic Radiology, Univ. Sheffield, United-Kingdom)

Local scientific organiser

Xavier Maître (U2R2M, CNRS, Univ. Paris-Sud, Orsay, France)

Scientific management assistant

Frédérique Foulon (LRMN, Univ. Claude Bernard, Lyon, France)
Patricia Odet (Lyon Ingénierie, Lyon, France)

Main topics

  • Human and animal airways
  • Modelling of the respiratory system
  • Standard lung imaging techniques
  • Basics of hyperpolarisation - production basics
  • Principles of magnetic resonance imaging
  • Magnet and gradient systems - MRI scanner design
  • Radiofrequency emission and reception - coil design
  • Basic pulse sequencing for hyperpolarised gases
  • Patient management and mechanical ventilation strategies
  • Human lung exploration with helium-3 magnetic resonance
  • Ventilation, diffusion, partial oxygen pressure, dynamic, and flow imaging

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Research and Training Network (RTN) - Marie Curie Actions - 6th Framework Program (2007-2010)

 
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